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KMID : 0356919760090020085
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Korean Journal of Anesthesiology
1976 Volume.9 No. 2 p.85 ~ p.89
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Serum Testosterone in Man during Halothane Anesthesia and Surgery
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Abstract
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The relationship between the Leydig cell of testis and the tropic hormones of the anterior pituitary gland has been inadequately explored in man because of methodological difficulties.
Ether anesthesia has been shown to increase testicular blood level of testosterone in man. Some report has appeared on the effect of anesthesia per so on sex hormone levels in human serum. As testosterone is one of the most important anabolic hormones, it would therefore serve as an index to hormonal response to stress in man.
Testosterone levels were measured by Oyama et al by competitive protein binding method. This study was done to investigate the effect of halothane anesthesia and surgery on human sex hormone by radioimmunoassay method.
Serum testosterone levels measured at pre=anesthetic period, 60 minutes after anesthesia and surgery, and full recovery from anesthesia were 4.18±1.64 ng/ml, 4.19±1.40 ng/ml and 3.74±1.65 ng/ml, respectively.
No statistical significance was noticed each other. The obtained value of testosterone was the lowest compared with the values reported by other authors.
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